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KMID : 0362919830010010005
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Journal of the Korean Society for Therapeutic Radiology and Oncology
1983 Volume.1 No. 1 p.5 ~ p.10
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An Experimental Study on Late Change of the Irradiated Lung
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Byun Hong-Sik
Park Charn-Il
Han Man-Chung
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Abstract
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To evaluate late change of irradiated lung, a total of 60 rats was irradiated on right lungfield with a single dose of 2000 rads using Co-60 teletherapy unit. Follow-up roentgenographic and histopathologic study was performed three, six and twelve months after irradiation in each group of 20 rats.
The results were as follows:
1. Chest roentgenographic findings in the order of frequency were pneumonic consolidation, atelectasis, and pleural effusion in 3-month follow-up group; atelectasis, fibrostreaky infiltration, and pneumonic consolidation in 6-month follow-up; and normal, and normal, and atelectasis in 12-months follow-up group.
2. Main histopathological findings were alveolar and interstitial exudates, and diffuse infiltration of inflammatory cells in 3-month follow-up group; thickening of interstitium and vascular wall in 6-month follow-up group; and interstitial fibrosis in 12-month follow-up group.
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KEYWORD
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